Rebuild

Description by Metabolic Maintenance
 
Maintaining bone health is a critical factor in maintaining mobility and independence as we age. Rebuild® is a full-spectrum, research-based formula designed to support bone health. It contains highly bioavailable forms of the vitamins and minerals needed to support the formation and maintenance of bone tissue. Adequate calcium and vitamin D, as part of a well-balanced diet, along with physical activity, support optimal bone health.
 
Uses: Bone is living tissue that is constantly being broken down and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone, resulting in deceased bone mineral density (BMD). It is assorted with back pain, stooped posture, and higher fracture risk. Osteoporosis affects men and women of all races but is especially prevalent in white or Asian postmenopausal women.
Rebuild® is based on a 2-year, double-blind, placebo-controlled study that measured spinal bone loss in postmenopausal women (1). The results showed that supplementation with calcium plus trace minerals (zinc, manganese, and copper) was far more effective in maintaining BMD than calcium alone.
 
Rebuild® also contains magnesium which is essential for the absorption of calcium, acts on crystal formation in bone cells, and impacts the activity of parathyroid hormone- a regulator of calcium homeostasis (2). 60% of the body’s magnesium is stored in bone. Magnesium deficiency results in lower BMD as magnesium is pulled out of bone for other biological functions.
 
Vitamin D3 stimulates absorption of calcium from the gut. Vitamin D status is related to BMD, and supplementation decreases bone turnover (3).
 
Vitamins K-1 and K-2 work synergistically with vitamin D to stimulate production and activation osteocalcin, a protein involved in bone mineralization (4). Osteocalcin is essential for pulling calcium out of the blood and into bone. In a recent 3-year study, low-dose vitamin K2 M7 decreased bone loss and increased bone strength in postmenopausal women (5).
 
Source Materials: Ascorbyl palmitate: ascorbic acid from corn sorbitol and palmitic acid from palm oil. Vitamin D3: lanolin from sheep’s wool. Vitamin K-1: chemical synthesis. Vitamin K-2 M7: fermentation of soy with Bacillus subtilis natto (all soy removed). Minerals are mined. Chelating agents include: malic acid, glucuronic acid, picolinic acid, and glycine (synthetic). Cellulose for capsules is derived from softwood tree pulp. All ingredients are non-GMO.
 
Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.
 
Recommendations: Take three capsules two times daily, or as directed by a healthcare professional.
 
Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.
 
California residents:
WARNING: Consuming this product can expose you to lead, which is known to the State of California to cause cancer and birth defects. For more information go to www.P65Warnings.ca.gov/food
 
References:
Strause, L., et. al.; Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals; J Nutr. 1994 Jul;124(7):1060-4.
Castiglioni, S. et.al.; Magnesium and osteoporosis: current state of knowledge and future research directions; Nutrients 2013 (5): 3022-33.
Lips, P., van Schoor NM; The effect of vitamin D on bone and osteoporosis; Best Pract Res Clin Endocrinol Metab 2011 Aug;25(4):585-91.
Weber, P.; Vitamin K and bone health; Nutrition 2001 Oct; 17(10):880-7.
Knapen, MH, et.al.; Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women; Osteoporosis Int. 2013 Se;24(90:2499-507.